Design of a novel LOX-1 receptor antagonist mimicking the natural substrate
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چکیده
منابع مشابه
Design of a novel LOX-1 receptor antagonist mimicking the natural substrate.
The lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), the major receptor for oxidized low-density lipoprotein (ox-LDL) in endothelial cells, is overexpressed in atherosclerotic lesions. LOX-1 specific inhibitors, urgently necessary to reduce the rate of atherosclerotic and inflammation processes, are not yet available. We have designed and synthesized a new modified oxidized phos...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2013
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2013.07.073